ACTOVEGIN®

Chemical name Actovegin Form: 5 ampoules of 5 ml / 50 pills of 200 mg Form description: Clear yellowish solution for injection / Glassy greenish-yellow film-coated tablets of a round biconvex shape Active substance: Actovegin (deproteinized hemoderivative of calf blood) Excipients (pills): Magnesium stearate – 2.0 mg, talc – 3.0 mg, povidone-K 90 – 10.0 mg, microcrystalline cellulose – 135.0 mg.; Coating: gum acacia – 6.8 mg, glycolic mineral wax – 0.1 mg, hypromellose phthalate – 29.45 mg, diethyl phthalate – 11.8 mg, quinoline yellow colorant – 2.0 mg, macrogol-6000 – 2.95 mg, povidone-K 30 – 1.54 mg, sucrose – 52.3 mg, talc – 42.2 mg, titanium dioxide – 0.86 mg Excipients (injections): Water for injection СAS Number: 63748-11-8 ATC code: B06AB Pharmacological action: Tissue regeneration stimulator Shelf life: 3 years. Do not use it beyond the expiration date printed on the package. Storage conditions: Store in a dry dark place at temperatures no higher than 25°C (77°F). Keep out of reach of children. Terms of Release: Over-the-counter Manufacturer: Takeda Pharmaceutical, Austria/Russia Third-party tested. View Certificate of Analysis: COA Actovegin What is Actovegin? Actovegin is a biologically active extract that enhances aerobic oxidation, absorption of glucose, and oxygen uptake in tissue. It is derived from the blood of young calves (under three months old) and undergoes an advanced ultrafiltration process to remove proteins and potentially harmful substances, including prions. What is Actovegin Used For? Actovegin may be used for the following applications: Malfunction of the blood circulation and trophic disorders of the brain; Impairment of peripheral blood circulation and associated diseases; Cognitive impairments such as dementia and post-stroke cognitive impairments; Diabetic neuropathy as part of complex therapy; Dermal transplants and acute and chronic wounds. Actovegin has also been used by athletes who wanted to speed up the recovery process and enhance physical performance and stamina. It is also deemed a great option to treat various sports injuries. More detailed information about the studies on the application can be found in the Research tab. What are the Benefits and Effects of Actovegin? Actovegin provides three primary effects (according to the manufacturer): Metabolic Effect It increases the absorption and utilization of oxygen. It impacts positively on the utilization and transport of glucose, which leads to improved cellular metabolism and lowers lactate formation in case of ischemia. Neuroprotective Effect The neuroprotective effect is attributed to its ability to improve the regulation of apoptosis processes and inflammation in the central and peripheral nervous systems and repair single-chain DNA. Microcirculatory Effect The microcirculatory effect is due to an increase in the speed of capillary blood flow, a decrease in pericapillary space, a decrease in the myogenic tone of the precapillary arterioles and capillary sphincters, a decrease in the degree of blood flow with an improved circulation of blood in the capillary bed, as well as stimulation of endothelial nitric oxide synthase function, which influences the microcirculatory bed. Is Actovegin Safe to Take? Actovegin should be taken with precautions in case of hypersensitivity to this or analogous drugs and their excipients. FAQ: Can I Overdose on Actovegin? No overdose cases have been reported with Actovegin. However, it is always recommended to follow the prescribed dosage and consult with a healthcare provider if you have concerns. What is Actovegin Composition? Actovegin is composed of various physiologically active ingredients, including: – Amino acids such as ornithine, leucine, alanine, glutamate, proline, glycine, taurine, and others; – Oligopeptides; – Lipids; – Oligosaccharides; – Nucleosides like adenosine and uridine; – Antioxidants; – Electrolytes including Na, Cl, K, Mg, Ca, F, Fe; – Microelements such as Cu, Si, Se, and Zn. Organic compounds make up 30% of the Actovegin extract. Where Can I Order Actovegin Online? You can order Actovegin online from different vendors. CosmicNootropic offers Actovegin in packs of 5x5ml ampoules and 50x200mg pills with worldwide shipping! Always research reputable sources before purchasing to ensure product quality. Actovegin is approved in 17 countries, including Russia, China, South Korea, Latvia, and others. You can order Actovegin with delivery to the USA, Europe, the UK, Asia, and many other regions through CosmicNootropic. What Is the Origin of Actovegin? The origin of Actovegin dates back to when Swiss shepherds observed that young calves healed injuries and regenerated tissue much faster than older calves. In 1957, Swiss scientists developed a highly purified extract from the blood of young calves, which evolved into the drug now known as Actovegin. Is Actovegin Banned by WADA? Actovegin caused a lot of discussion and speculation after it was used by several athletes at the Sydney Olympic Games and Tour de France in 2000. The drug was suspected to have doping effects. However, the World Anti-Doping Agency (WADA) has not included Actovegin in its list of prohibited substances. Some studies show that in order to induce considerable performance enhancement effects with Actovegin, one has to exceed the permitted injectable amount of 50 ml every 6 hours.