AFOBAZOLE ® (FABOMOTIZOLE)

Buy Afobazole® (Fabomotizole) Online! Afobazole, also known as Fabomotizole, is a selective non-benzodiazepine anxiolytic launched in the early 2000s. It produces anxiolytic and neuroprotective effects without sedative or muscle relaxant actions. Chemical name Fabomotizole Form: 30 pills of 10mg / 60 pills of 10mg Form description: Bevel-edged pills of flat-cylindrical shape in white or light cream color. Active substance: Fabomotizole 10mg Excipients: Potato starch, microcrystalline cellulose, lactose, povidone, magnesium stearate. СAS Number: 173352-21-1 ATC code: N05BX Pharmacological action: Anxiolytic Shelf life: 2 years. Do not use it beyond the expiration date printed on the package. Storage conditions: Store in a dry dark place at temperatures no higher than 25°C (77°F). Keep in a safe place out of reach of children. Terms of release: Over-the-counter Manufacturer: OTCPharm / PharmStandard What is Afobazole? Afobazole is a novel anxiolytic drug with nootropic properties, used to treat anxiety and cardiac disorders. One of the most important advantages of Afobazole (Fabomotizole) over benzodiazepines is that it does not form dependence and has fewer side effects. What is Afobazole Used for? Afobazole (Fabomotizole) is used to treat the following symptoms: Generalized anxiety disorder symptoms, e.g. bad feelings, tensions in the body, irritability, tearfulness, fearfulness, etc.; Adjustment disorders; Various somatic (psychophysiological) disorders, e.g. asthma, irritable bowel syndrome, systemic lupus erythematosus, ischemic heart diseases; Sleep disorders caused by anxiety; Premenstrual syndrome; Alcohol withdrawal and nicotine withdrawal syndrome; Neurocirculatory dystonia; Neurasthenia. What are Afobazole Benefits and Effects? The benefits of the drug are achieved mostly through the combination of its anxiolytic and light-stimulating effects. Afobazole can: Reduce anxiety, bad foreboding, and fears; Lower irritability, tension (fearfulness, tearfulness, anxiety, inability to relax, insomnia, and fear); Help with depressive mood, somatic manifestations of anxiety (muscular, sensory, cardiovascular, respiratory, and gastrointestinal symptoms); Elevate autonomic disorders (dry mouth, sweating, and dizziness); Reduce cognitive disorders (difficulty concentrating and poor memory), including those arising from stress. Is Afobazole Safe to Take? The treatment with Afobazole is usually well-tolerated by patients. The drug is not habit-forming and does not cause withdrawal after cessation. However there are certain contraindications to its use namely: hypersensitivity to the components of the drug (intolerance to galactose, lactase deficiency, and glucose-galactose malabsorption); age below 18 years old; pregnancy and lactation. FAQ: Where Can I Order Afobazole Online? You can order Afobazole online from different vendors. CosmicNootropic offers Afobazole in packs of 30x10mg and 60x10mg pills with worldwide shipping! Always be sure to do your research before purchasing any nootropic supplement to ensure you are getting a quality product. You can order Afobazole and get it delivered to the USA, Europe, the UK, Asia, and many other destinations via CosmicNootropic. What is the Afobazole Mechanism of Action? Afobazole mechanism of action is different from that of benzodiazepines. It is not a benzodiazepine receptor site agonist; at the same time, it prevents stress-induced changes in the GABA-benzodiazepine receptor complex and restores its sensitivity to endogenous inhibitory mediators. The drug acts on σ1 receptors, melatonin MT1 and MT3 receptors, and was shown to reversibly inhibit MAO-A. Afobazole also increases the bioenergetic potential of neurons, and restores and protects nerve cells. Besides, it has some neurotrophic properties, although they are not as pronounced as in Stresam, another non-sedative anxiolytic. In studies on rats, Afobazole prevented stress-induced BDNF decrease and it increased NGF and BDNF content in hippocampal HT22 cells culture. Can I Overdose on Afobazole? In case of overdose, the sedative effect and sleepiness are possible. These side effects can be treated with caffeine. How Was Afobazole Discovered? Afobazole was discovered at the beginning of the 2000s in Russia at the Zakusov Institute of Pharmacology. This institute is also known for its discovery of Noopept, Ladasten (Bromantane), and Selank. Afobazole is a popular anxiolytic that can now be bought over the counter in almost every Russian pharmacy. What Makes Afobazole So Special? Afobazole does not have sedative, hypnotic, or muscle relaxant action unlike many other anti-anxiety medications. Along with that, it does not form dependence in any dosage. Besides, Afobazole studies in models of local and global ischemia have revealed the neuroprotective effects of the drug.