TRIMETAZIDINE

Buy Trimetazidine Online! Trimetazidine is an anti-ischemic metabolic agent that improves myocardial glucose utilization through the inhibition of fatty acid metabolism. It is used as a long-term treatment for angina pectoris. Save with the volume discount! Synonyms 1-(2,3,4-trimybenzyl)piperazine / Vastarel Form: 60 pills of 35mg Form description: Pink round biconvex film-coated tablets. On the cross-section of the tablet, the core is white or almost white. Active ingredient: Trimetazidine dihydrochloride – 35 mg Excipients: Hypromellose – 90 mg, calcium hydrophosphate dihydrate – 141 mg, magnesium stearate – 3 mg, colloidal silicon dioxide – 1 mg. Film coating: water-based pink gloss – 7 mg (hypromellose, stearic acid, macrogol-6000, glycerol, titanium dioxide, iron dye red oxide). СAS Number: 5011-34-7 ATC code: С01ЕВ15 Pharmacological action: Antihypoxic agent Shelf life: 3 years. Do not use it beyond the expiration date printed on the package. Storage conditions: Store in a dry dark place at temperatures no higher than 25°C (77°F). Keep out of reach of children. Terms of release: Over-the-counter Manufacturer: Ozon Pharmaceutics/Russia What is Trimetazidine? Trimetazidine is an anti-hypoxic drug stimulating the metabolism of the myocardium and sensorineural organs in case of ischemia. Its active ingredient is trimetazidine which was the first cytoprotective anti-ischemic agent developed and marketed by Laboratoires Servier (France). Trimetazidine is usually prescribed as a long-term treatment of angina pectoris, and in some countries (including France) for tinnitus and dizziness. What is the Mechanism of Action of Trimetazidine? Trimetazidine inhibits beta-oxidation of fatty acids by blocking long-chain 3-ketoacyl-CoA thiolase, which enhances glucose oxidation. By preserving energy metabolism in cells exposed to hypoxia or ischemia, trimetazidine prevents a decrease in intracellular ATP levels, thereby ensuring the proper functioning of ionic pumps and transmembrane sodium-potassium flow whilst maintaining cellular homeostasis. What are the Benefits and Effects of Trimetazidine? Trimetazidine can stimulate the metabolism of cardiomyocytes and brain neuronal cells, thereby stabilizing oxygen consumption and myocardial contractility. In patients with angina pectoris, the drug has a pronounced effect of reducing blood pressure and regulating the heart rate after several weeks of administration. Controlled studies in angina patients have shown that trimetazidine increases coronary flow reserve, thereby delaying the onset of ischemia. It improves left ventricular function in diabetic patients with coronary heart disease. Recently, it has been shown to be effective in patients with heart failure of different etiologies. What is Trimetazidine Used For? Trimetazidine is prescribed to treat coronary heart disease with angina pectoris manifestations. The drug provides symptomatic treatment and prevents vascular vertigo, tinnitus, hearing impairment, and chorioretinal vascular disorders. Trimetazidine can be administered both as a monotherapy and in combination with other antianginals if they do not provide the required effect. Is Trimetazidine Banned in Sports? The substance is banned by the World Anti-Doping Association (WADA). It is believed to enhance endurance and performance in sports as it can make energy metabolism more efficient and improve tissue oxygenation. During the Olympics 2022, Kamila Valieva, a figure skater of the Russian Olympic Committee, had been tested positive for trimetazidine. Where Can I Order Trimetazidine Online? You can buy Trimetazidine online from different vendors. CosmicNootropic offers Trimetazidine in packs of 60x35mg pills. We offer worldwide shipping with volume discounts! Always be sure to do your research before purchasing any nootropic supplement to ensure you are getting a quality product. You can order Trimetazidine and get it delivered to the USA, Europe, the UK, Asia, and many other regions and countries via CosmicNootropic. Check out more Adaptogens at our store!